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Livres
Articles (47)
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Engineering IL-2 to Give New Life to T Cell Immunotherapy

Overwijk, Willem W., Tagliaferri, Mary A., Zalevsky, Jonathan

Journal:

Annual Review of Medicine

Année:

2021

Fichier:

PDF, 509 KB

2021

Adjuvants for peptide-based cancer vaccines

Khong, Hiep, Overwijk, Willem W.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2016

Langue:

english

Fichier:

PDF, 705 KB

english, 2016

Vaccinating with Stem Cells to Stop Cancer

Hailemichael, Yared, Singh, Manisha, Overwijk, Willem

Journal:

Trends in Molecular Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 444 KB

english, 2018

T Helper 17 Cells Promote Cytotoxic T Cell Activation in Tumor Immunity

Natalia Martin-Orozco, Pawel Muranski, Yeonseok Chung, Xuexian O. Yang, Tomohide Yamazaki, Sijie Lu, Patrick Hwu, Nicholas P. Restifo, Willem W. Overwijk, Chen Dong

Journal:

Immunity

Année:

2009

Langue:

english

Fichier:

PDF, 924 KB

english, 2009

Identification of a feed-back circuit regulating the immune response and operating under different conditions of immunosuppression

Vincenzo Bronte, Federica Pericle, Michael Wang, Willem W. Overwijk, Nicholas P. Restifo

Journal:

Immunology Letters

Année:

1997

Langue:

english

Fichier:

PDF, 184 KB

english, 1997

Antigen-specific tumor vaccine efficacy in vivo against prostate cancer with low class I MHC requires competent class II MHC

Yilin C. Neeley, Kevin T. McDonagh, Willem W. Overwijk, Nicholas P. Restifo, Martin G. Sanda

Journal:

The Prostate

Année:

2002

Langue:

english

Fichier:

PDF, 161 KB

english, 2002

Breaking tolerance in cancer immunotherapy: time to ACT

Willem W Overwijk

Journal:

Current Opinion in Immunology

Année:

2005

Langue:

english

Fichier:

PDF, 145 KB

english, 2005

Functions of γC cytokines in immune homeostasis: Current and potential clinical applications

Willem W. Overwijk, Kimberly S. Schluns

Journal:

Clinical Immunology

Année:

2009

Langue:

english

Fichier:

PDF, 384 KB

english, 2009

Identification of a Kb-restricted CTL Epitope of β-Galactosidase: Potential Use in Development of Immunization Protocols for “Self” Antigens

Willem W. Overwijk, Deborah R. Surman, Kangla Tsung, Nicholas P. Restifo

Journal:

Methods

Année:

1997

Langue:

english

Fichier:

PDF, 121 KB

english, 1997

Survivin DNA vaccine generated specific antitumor effects in pancreatic carcinoma and lymphoma mouse models

Kuichun Zhu, Hong Qin, Soung-Chul Cha, Sattva S. Neelapu, Willem Overwijk, Gregory A. Lizee, James L. Abbruzzese, Patrick Hwu, Laszlo Radvanyi, Larry W. Kwak, David Z. Chang

Journal:

Vaccine

Année:

2007

Langue:

english

Fichier:

PDF, 466 KB

english, 2007

Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy

Prakash Thapa, Guodong Zhang, Chengfeng Xia, Alexander Gelbard, Willem W. Overwijk, Chengwen Liu, Patrick Hwu, David Z. Chang, Amy Courtney, Jagannadha K. Sastry, Peng G. Wang, Chun Li, Dapeng Zhou

Journal:

Vaccine

Année:

2009

Langue:

english

Fichier:

PDF, 434 KB

english, 2009

Highly attenuated modified vaccinia virus Ankara (MVA) as an effective recombinant vector: a Murine tumor model

Miles W. Carroll, Willem W. Overwijk, Ronald S. Chamberlain, Steven A. Rosenberg, Bernard Moss, Nicholas P. Restifo

Journal:

Vaccine

Année:

1997

Langue:

english

Fichier:

PDF, 1.18 MB

english, 1997

Creating therapeutic cancer vaccines: notes from the battlefield

Willem W Overwijk, Nicholas P Restifo

Journal:

Trends in Immunology

Année:

2001

Langue:

english

Fichier:

PDF, 34 KB

english, 2001

Harnessing the Power of the Immune System to Target Cancer

Lizée, Gregory, Overwijk, Willem W., Radvanyi, Laszlo, Gao, Jianjun, Sharma, Padmanee, Hwu, Patrick

Journal:

Annual Review of Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2013

Mining the mutanome: developing highly personalized Immunotherapies based on mutational analysis of tumors

Willem W Overwijk, Ena Wang, Francesco M Marincola…

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2013

Langue:

english

Fichier:

PDF, 267 KB

english, 2013

Cancer vaccines: Trafficking of tumor-specific T cells to tumor after therapeutic vaccination

Hailemichael, Yared, Overwijk, Willem W.

Journal:

The International Journal of Biochemistry & Cell Biology

Année:

2014

Langue:

english

Fichier:

PDF, 758 KB

english, 2014

Antigen Expression by Dendritic Cells Correlates with the Therapeutic Effectiveness of a Model Recombinant Poxvirus Tumor Vaccine

Vincenzo Bronte, Miles W. Carroll, Theresa J. Goletz, Michael Wang, Willem W. Overwijk, Francesco Marincola, Steven A. Rosenberg, Bernard Moss and Nicholas P. Restifo

Journal:

Proceedings of the National Academy of Sciences

Année:

1997

Langue:

english

Fichier:

PDF, 1.02 MB

english, 1997

Vaccination with a Recombinant Vaccinia Virus Encoding a "self" Antigen Induces Autoimmune Vitiligo and Tumor Cell Destruction in Mice: Requirement for Cd4+T Lymphocytes

Willem W. Overwijk, David S. Lee, Deborah R. Surman, Kari R. Irvine, Christopher E. Touloukian, Chi-Chao Chan, Miles W. Carroll, Bernard Moss, Steven A. Rosenberg and Nicholas P. Restifo

Journal:

Proceedings of the National Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 1.62 MB

english, 1999

Characterization of the Inflammatory Microenvironment and Identification of Potential Therapeutic Targets in Wilms Tumors

Maturu, Paramahamsa, Overwijk, Willem W., Hicks, John, Ekmekcioglu, Suhendan, Grimm, Elizabeth A., Huff, Vicki

Journal:

Translational Oncology

Année:

2014

Langue:

english

Fichier:

PDF, 2.71 MB

english, 2014

Dose-Dependent and Schedule-Dependent Effects of Interleukin-12 on Antigen-Specific CD8 Responses

O'Toole, Margot, Swiniarski, Holly, Overwijk, Willem W., Restifo, Nicholas P., Dorner, Andrew J., Wolf, Stanley F., Sturmhoefel, Knut

Journal:

Journal of Interferon & Cytokine Research

Année:

2000

Langue:

english

Fichier:

PDF, 234 KB

english, 2000

The Duality of Fgl2 - Secreted Immune Checkpoint Regulator Versus Membrane-Associated Procoagulant: Therapeutic Potential and Implications

Hu, Jiemiao, Yan, Jun, Rao, Ganesh, Latha, Khatri, Overwijk, Willem W., Heimberger, Amy B., Li, Shulin

Journal:

International Reviews Of Immunology

Année:

2014

Langue:

english

Fichier:

PDF, 538 KB

english, 2014

Human CD4+ T cells spontaneously detect somatic mutations in cancer cells

Overwijk, Willem W

Journal:

Nature Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2015

Photo-electric cells

Overwijk, Willem W

Journal:

Journal of the Institution of Electrical Engineers

Année:

1957

Langue:

english

Fichier:

PDF, 355 KB

english, 1957

Peptide-based anticancer vaccines

Hailemichael, Yared, Overwijk, Willem W

Journal:

OncoImmunology

Année:

2013

Langue:

english

Fichier:

PDF, 611 KB

english, 2013

Chemical Castration of Melanoma Patients Does Not Increase the Frequency of Tumor-specific CD4 and CD8 T Cells After Peptide Vaccination

Vence, Luis M., Wang, Chiyu, Pappu, Himabindu, Anson, Ryan E., Patel, Tejal A., Miller, Priscilla, Bassett, Roland, Lizee, Gregory, Overwijk, Willem W., Komanduri, Krishna, Benjamin, Cara, Alvarado, G

Journal:

Journla of Immunotherapy

Année:

2013

Langue:

english

Fichier:

PDF, 423 KB

english, 2013

Intratumoral immunotherapy for melanoma

Singh, Manisha, Overwijk, Willem W.

Journal:

Cancer Immunology, Immunotherapy

Année:

2015

Langue:

english

Fichier:

PDF, 666 KB

english, 2015

Conference Scene: Immune effector mechanisms in tumor immunity

Sikora, Andrew G, Hailemichael, Yared, Overwijk, Willem W

Journal:

Immunotherapy

Année:

2012

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2012

Tumor immunology and cancer immunotherapy: summary of the 2014 SITC primer

Page, David B., Bourla, Ariel Bulua, Daniyan, Anthony, Naidoo, Jarushka, Smith, Eric, Smith, Melody, Friedman, Claire, Khalil, Danny N., Funt, Samuel, Shoushtari, Alexander N., Overwijk, Willem W., Sh

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 467 KB

english, 2015

Dendritic Cells Infected with PoxvIn Vitro iruses Encoding MART-1/ Melan A Sensitize T Lymphocytes In Vitro

Kim, Christina J., Prevett, Tracy, Cormie, Janice, Overwijk, Willem, Roden, Matthew, Restifo, Nicholas P., Rosenberg, Steven A., Marincola, Francesco M.

Journal:

Journal of Immunotherapy

Année:

1997

Fichier:

PDF, 989 KB

1997

T-Cell Receptor Gene Therapy of Established Tumors in a Murine Melanoma Model

Abad, John D., Wrzensinski, Claudia, Overwijk, Willem, De Witte, Moniek A., Jorritsma, Annelies, Hsu, Cary, Gattinoni, Luca, Cohen, Cyrille J., Paulos, Chrystal M., Palmer, Douglas C., Haanen, John B.

Journal:

Journal of Immunotherapy

Année:

2008

Langue:

english

Fichier:

PDF, 297 KB

english, 2008

Cloning and Characterization of the Genes Encoding the Murine Homoloties of the Human Melanoma Antigens MARTI and gp100

Zhai, Yifan, Yang, James C., Spiess, Paul, Nishimura, Michael I., Overwijk, Willem W., Roberts, Bruce, Restifo, Nicholas P., Rosenberg, Steven A.

Journal:

Journal of Immunotherapy

Année:

1997

Fichier:

PDF, 883 KB

1997

Agonistic Antibody to CD40 Boosts the Antitumor Activity of Adoptively Transferred T Cells In Vivo

Liu, Chengwen, Lewis, Carol M., Lou, Yanyan, Xu, Chunyu, Peng, Weiyi, Yang, Yan, Gelbard, Alexander H., Lizée, Gregory, Zhou, Dapeng, Overwijk, Willem W., Hwu, Patrick

Journal:

Journal of Immunotherapy

Année:

2012

Langue:

english

Fichier:

PDF, 272 KB

english, 2012

Differential Expression of the G-Protein–Coupled Formyl Peptide Receptor in Melanoma Associates With Aggressive Phenotype

Chakravarti, Nitin, Peddareddigari, Vijay G. R., Warneke, Carla L., Johnson, Marcella M., Overwijk, Willem W., Hwu, Patrick, Prieto, Victor G.

Journal:

American Journal of Dermatopathology

Année:

2013

Langue:

english

Fichier:

PDF, 973 KB

english, 2013

Antitumor Activity Mediated by CpG

Lou, Yanyan, Liu, Chengwen, Lizée, Gregory, Peng, Weiyi, Xu, Chunyu, Ye, Yang, Rabinovich, Brian A., Hailemichael, Yared, Gelbard, Alexander, Zhou, Dapeng, Overwijk, Willem W., Hwu, Patrick

Journal:

Journal of Immunotherapy

Année:

2011

Langue:

english

Fichier:

PDF, 730 KB

english, 2011

Temporally Programmed CD8α+ DC Activation Enhances Combination Cancer Immunotherapy

Tzeng, Alice, Kauke, Monique J., Zhu, Eric F., Moynihan, Kelly D., Opel, Cary F., Yang, Nicole J., Mehta, Naveen, Kelly, Ryan L., Szeto, Gregory L., Overwijk, Willem W., Irvine, Darrell J., Wittrup, K

Journal:

Cell Reports

Année:

2016

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2016

Role of Cyclooxygenase-2 Pathway in Creating an Immunosuppressive Microenvironment and in Initiation and Progression of Wilms' Tumor

Maturu, Paramahamsa, Jones, Devin, Ruteshouser, E. Cristy, Hu, Qianghua, Reynolds, Joseph M, Hicks, John, Putluri, Nagireddy, Ekmekcioglu, Suhendan, Grimm, Elizabeth A., Dong, Chen, Overwijk, Willem W

Journal:

Neoplasia

Année:

2017

Langue:

english

Fichier:

PDF, 2.80 MB

english, 2017

Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy

Hodges, Tiffany R., Ott, Martina, Xiu, Joanne, Gatalica, Zoran, Swensen, Jeff, Zhou, Shouhao, Huse, Jason T., de Groot, John, Li, Shulin, Overwijk, Willem W., Spetzler, David, Heimberger, Amy B.

Journal:

Neuro-Oncology

Année:

2017

Langue:

english

Fichier:

PDF, 667 KB

english, 2017

Synthetic Poly(L-Glutamic Acid)-conjugated CpG Exhibits Antitumor Efficacy With Increased Retention in Tumor and Draining Lymph Nodes After Intratumoral Injection in a Mouse Model of Melanoma

Ma, Qing, Zhou, Dapeng, DeLyria, Elizabeth S., Wen, Xiaoxia, Lu, Wei, Thapa, Prakash, Liu, Chengwen, Li, Dan, Bassett, Roland L., Overwijk, Willem W., Hwu, Patrick, Li, Chun

Journal:

Journal of Immunotherapy

Année:

2017

Langue:

english

Fichier:

PDF, 736 KB

english, 2017

Multifaceted role of BTLA in the control of CD8+ T cell fate after antigen encounter

Ritthipichai, Krit, Haymaker, Cara, Martinez-Paniagua, Melisa, Aschenbrenner, Andrew, Yi, Xiaohui, Zhang, Minying, Kale, Charuta, Hailemichael, Yared, Overwijk, Willem W., Vence, Luis, Roszik, Jason,

Journal:

Clinical Cancer Research

Année:

2017

Langue:

english

Fichier:

PDF, 6.39 MB

english, 2017

Cancer vaccines in the era of checkpoint blockade: the magic is in the adjuvant

Overwijk, Willem W

Journal:

Current Opinion in Immunology

Année:

2017

Langue:

english

Fichier:

PDF, 540 KB

english, 2017

Immune cell profiling in cancer: molecular approaches to cell-specific identification

Lyons, Yasmin A., Wu, Sherry Y., Overwijk, Willem W., Baggerly, Keith A., Sood, Anil K.

Journal:

npj Precision Oncology

Année:

2017

Langue:

english

Fichier:

PDF, 602 KB

english, 2017

Simultaneous inhibition of hedgehog signaling and tumor proliferation remodels stroma and enhances pancreatic cancer therapy

Zhao, Jun, Wang, Huamin, Hsiao, Cheng-Hui, Chow, Diana S-L., Koay, Eugene J., Kang, Yaan, Wen, Xiaoxia, Huang, Qian, Ma, Ying, Bankson, James A., Ullrich, Stephen E., Overwijk, Willem, Maitra, Anirban

Journal:

Biomaterials

Année:

2018

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2018

The immune system in cancer metastasis: friend or foe?

Janssen, Louise M.E., Ramsay, Emma E., Logsdon, Craig D., Overwijk, Willem W.

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2017

Langue:

english

Fichier:

PDF, 479 KB

english, 2017

L-tyrosine is a promising cancer vaccine adjuvant

Khong, Hiep, Sharma, Meenu, Dai, Zhimin, Singh, Manisha, Hailemichael, Yared, Overwijk, Willem

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 244 KB

english, 2015

Induction of potent systemic anti-melanoma immunity through intratumoral CD40 activation and checkpoint blockade

Singh, Manisha, Dai, Zhimin, Khong, Hiep, Vianden, Christina, Cantwell, Mark, Overwijk, Willem

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 209 KB

english, 2015

Natural Splice Variant of MHC Class I Cytoplasmic Tail Enhances Dendritic Cell-Induced CD8+ T-Cell Responses and Boosts Anti-Tumor Immunity

Rodríguez-Cruz, Tania G., Liu, Shujuan, Khalili, Jahan S., Whittington, Mayra, Zhang, Minying, Overwijk, Willem, Lizée, Gregory, Moura, Ivan Cruz

Journal:

PLoS ONE

Année:

2011

Langue:

english

Fichier:

PDF, 2.05 MB

english, 2011

Stromal Modulation Reverses Primary Resistance to Immune Checkpoint Blockade in Pancreatic Cancer

Zhao, Jun, Xiao, Zhilan, Li, Tingting, Chen, Huiqin, Yuan, Ying, Wang, Y. Alan, Hsiao, Cheng-Hui, Chow, Diana S-L., Overwijk, Willem W., Li, Chun

Journal:

ACS Nano

Année:

2018

Langue:

english

Fichier:

PDF, 2.85 MB

english, 2018